Structural biology


Protein crystallography – Bioscience

Rigaku Micromax-007

X-ray generator

Biocity 5th floor

OpenIris

HyPix-600

Hybrid Photon Counting X-ray Detector

Biocity 5th floor

OpenIris

Oxford Cryosystems 800

Data collection at cryogenic temperatures (100K) and the testing for cryoprotectants

Biocity 5th floor

OpenIris

Formulatrix RI54

Plate hotel with crystal imaging system

Biocity 5th floor

OpenIris

XtalCheck

Automated in situ X-ray crystallography Screen protein crystals on a single crystal X-ray diffractometer

Biocity 5th floor

OpenIris

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Oryx 4 Crystallization robot

High-throughput crystallisation robot for sitting drops, micro-batch under oil, microseeding, and optimisation of crystallization conditions.

Biocity 5th floor

OpenIris

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Incubators for crystallization plates

Maintained at 4 and 16 °C

Biocity 5th floor

OpenIris

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Protein crystallography – Åbo Akademi

PX Scanner

X-rayscreening of crystals directly from 96-well crystallization platestotest diffraction. Protein and salt crystals can be distinguished.

Biocity 3rd floor

OpenIris

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NT8 (new version 4)

Nanoliter-volume all-in-oneliquid handler for setting drops and well solutions for crystallization screens, also Lipidic Cubic Phase (LCP) experiments.

Biocity 3rd floor

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ROCK IMAGER 360 (Formulatrix)

Automatic imaging of protein crystals and monitoring crystal growth on 96-well crystallization plates at RT. Black and white images. UV-detection. Images can be accessed remotely using IceBear (https://www.icebear.fi).

Biocity 3rd floor

Reservation through contact person

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RockImager (Formulatrix RI-54) with connection to NT8

Automatic imaging of protein crystals and monitoring crystal growth on 96-well crystallization plates at +4 °C. Images can be accessed remotely using IceBear (https://www.icebear.fi).

Biocity 3rd floor

Reservation through contact person

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Incubators for crystallization plates

Accurate temperature control.Two different incubators: at 22 and 10°C. Vibration free.

Biocity 3rd floor

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CryoEM sample preparation

GloQube Plus Glow discharge system (Quorum Technologies)

Easy glow discharging of TEM grids and support films.

Biocity 3rd floor

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Vitrobot Mark IV System (Thermo Scientific)

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Semi-automated vitrification of samples for cryo-EM.

Biocity 3rd floor

OpenIris

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Structural computational work

Computers (structural computational work)

Major crystallographic software for protein structure solution (Phenix, CCP4), molecular graphics (Coot, Chimera, CCP4MG, PyMol), CrysAlis, Olex2 and AutoChem for small-molecule crystallography, Linux/Windows operating systems.

Biocity 5th floor

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Computers (structural bioinformatics)

Linux/windows work stations with 3D stereo option and software needed for structural bioinformatics tasks.

Biocity 3rd floor

Reservation through contact person

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